People on a skiff shot at the USS Ashland approximately 330 nautical miles off the coast of Djibouti.
The Ashland shot back, the U.S. Fifth Fleet said. The skiff caught fire and the people abandoned the skiff.
The Ashland deployed rigid-hull inflatable boats to assist the six suspected pirates in the water near their skiff. They were brought on board the Ashland and received medical care.
There were no injuries to the Ashland crew and no apparent damage to the ship, the U.S. Fifth Fleet said.