Republican candidate Rand Paul has won the Kentucky Senate race, CNN projects, beating out Democrat Jack Conway to become the first Tea Party candidate to win in the Senate.

Elsewhere, CNN projects that Vermont Democratic incumbent Sen. Patrick Leahy has won re-election to a seventh term, beating out Republican nominee Len Britton in the Senate race.

South Carolina incumbent Republican Sen. Jim DeMint has won his bid for re-election to a second term, CNN projects, beating out surprise Democratic nominee Alvin Greene.

Republican Dan Coats has defeated Democratic Rep. Brad Ellsworth to win Indiana's Senate race, CNN projects, to take the seat vacated by Democratic Sen. Evan Bayh.