Gulf oil spill - BP could undertake what some say is a pivotal moment for the London-based oil giant to contain the gushing oil in the Gulf of Mexico - a maneuver called "top kill." The goal is to seal a leak by covering it with liquids that are heavier than water. BP's top official told CNN the oil company will make a decision later Wednesday on whether to start the procedure. Interior Secretary Ken Salazar also is scheduled to testify about the spill at a Capitol Hill hearing at 10 a.m. ET Wednesday.
Atlantis landing - The space shuttle Atlantis is set to land Wednesday morning, ending the orbiter's stellar 25-year career. The shuttle, fresh off a trip to the international space station,¬†was expected to land at Kennedy Space Center in Florida, weather permitting.
Ferguson appearance - Sarah Ferguson, the Duchess of York, is scheduled to appear at a book convention in New York on Wednesday morning, undeterred by a scandal that she allegedly offered to sell access to her former husband, Britain's Prince Andrew.
Police discuss Arizona law - Police chiefs from about a dozen cities meet with U.S. Attorney General Eric Holder on Wednesday to express their opposition to a controversial Arizona immigration law. The chiefs say the law will drive a wedge between police officers and immigrant communities, undoing years of trust-building on both sides.
Blood donations and gay men - A Food and Drug Administration rule from the 1980s says if you are a male who has had sexual contact with another male, even once, since 1977, you shouldn‚Äôt give blood. The lifetime ban on blood donations from men who have had sex with men is rooted in the fear of HIV/AIDS.¬† But better testing of blood is removing doubts about whether a blood donor is carrying HIV, and earlier this year a group of U.S. senators wrote to the FDA urging a review of what they called the ‚Äúoutdated, medically and scientifically unsound‚ÄĚ criteria.¬†CNN's Madison Park reports.